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A Study of PDR001 in Combination With CJM112, EGF816, Ilaris® (Canakinumab) or Mekinist® (Trametinib)

Novartis Pharmaceuticals · 2016
ClinicalTrials.gov · Datasets · License: Public Domain · 2016
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biomarkerscolorectal-cancerimmunomodulationimmunotherapyrectal-cancertriple-negative-breast-cancer
The purpose of this study was to combine the PDR001 checkpoint inhibitor with each of four agents with immunomodulatory activity to identify the doses and schedule for combination therapy and to preliminarily assess the safety, tolerability, pharmacological and clinical activity of these combinations.
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