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Refining Genetic Instruments for Dietary Intake Mendelian Randomization Using Phenome-Wide Association Studies
Most Mendelian randomization (MR) of dietary intake use the full set of genome-wide significant (GWS) variants in the instrumental variable (IV), likely biasing causal estimates due to pleiotropy. To characterize the common methods to handle pleiotropy in dietary intake MR, we conducted a scoping re
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