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Granzyme A amplifies human neutrophil pyroptosis

Kasperkiewicz P et al.
Europe PMC · Papers · License: CC BY 4.0
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biomedicallife-science
Abstract Neutrophil granule serine proteases contribute to antimicrobial defence and regulate inflammatory cell death programs. Granzyme A (GrA) expression in neutrophils is controversial and its role in neutrophil cell death remains unknown. Here, we show that pharmacological inh
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