HAL (France)
open access
Intoxication of antibiotic persisters by host RNS inactivates their efflux machinery during infection
The host environment is of critical importance for antibiotic efficacy. By impacting bacterial machineries, stresses encountered by pathogens during infection promote the formation of phenotypic variants that are transiently insensitive to the action of antibiotics. It is assumed that these recalcit
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