HAL (France)
open access
Themis controls T cell activation, effector functions, and metabolism of peripheral CD8+ T cells
Themis is important in regulating positive selection of thymocytes during T cell development, but its role in peripheral T cells is less understood. Here, we investigated T cell activation and its sequelae using a tamoxifen-mediated, acute Themis deletion mouse model. We find that proliferation, eff
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