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Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

University of Wisconsin, Madison · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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The purpose of this research is to demonstrate that mild stimulation of a nerve (trigeminal nerve) in the head can modulate blood flow in the brain. The modulated blood flow will restore the flow of cerebrospinal fluid (CSF) and this in turn can help improve waste clearance in the brain and prevent build up that may lead to disease.
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