Success of Endodontic Regenerative Approaches in Anterior and Posterior Immature Non Vital Teeth

Aim of the Study To compare between anterior and posterior immature non vital teeth regarding: 1. Primary outcome: Resolution of apical periodontitis. 2. Secondary outcome: a) Increase in root length b) Increase in root width c) Decrease in apical area Using the following techniques: 1. Blood clot revascularization (BC). 2. Platelet-rich fibrin (PRF). Methods: 1. Diagnosis: Diagnostic data was collected \& recorded in a medical \& dental history sheet. A full history of the chief complaint was recorded including the intensity, nature, quality, onset, location, duration, course as well as initiating \& relieving factors of pain (if present). Clinical Examination: * Visual examination using mirror \& probe to detect caries, previous restorations or discoloration. - Examination of the Intraoral tissues for the detection of any swelling or sinus tract related to the tooth. * Palpation, Percussion, Bite \& Mobility tests was done to evaluate the periapical \& periodontal status of the involved tooth. * Periodontal probing of pocket depth was recorded for each of the involved teeth at 6 points: Mesiobuccally, Mid buccally, Distobuccally, Mesiolingually, Mid lingually \& Distolingually. * Pulp Sensibility tests, both Thermal (cold) \& Electrical was done \& recorded for the involved tooth as well as the contralateral tooth, in order to affirm the diagnosis as well as to serve as a reference for follow up. Radiographic examination: * An Intraoral periapical digital radiograph with standardized paralleling angle technique using XCP film holder \& standardized exposure settings (60 kV, 7 mA \& 0.160) was taken pre-operatively for the involved tooth using a size 2 PSP imaging plate. * Pre-operative CBCT with a limited field of view (40×40) was done in which the lesion size, bone density in the area of periapical lesion \& normal adjoining bony regions, \& the length \& width of the roots along with the diameter of the apex will be measured.