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Redox-Controlled Site-Specific O‑Sulfation Facilitated Diversity-Oriented Chemoenzymatic Synthesis of Chondroitin Sulfates A/C/E and Chimeric Chondroitin Sulfates

Yan Zhang (8098) et al.
Figshare · Datasets · License: CC BY-NC 4.0
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biochemistrycomputational-biologyinorganic-chemistryplant-biology
The biological functions of chondroitin sulfate (CS) are strongly influenced by its sulfation pattern. However, the limited site selectivity of currently available sulfotransferases has made it challenging to access CS oligosaccharides with diverse sulfation patterns. Herein, we report a redox-contr
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