bioRxiv / medRxiv
open access
CC BY-ND 4.0
Cell cycle control of chromatin creates a therapeutic window for epigenetic therapy in tumors
The relationship between cell cycle length and differentiation competence is well established in developmental biology, particularly in embryonic stem cells, where a short G1 phase maintains pluripotency and G1 lengthening permits lineage commitment. Whether this principle operates in cancer cells,
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