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Comparison of the Distribution of Fitness Effects Across Primates

Sendrowski, J. et al.
bioRxiv / medRxiv · Papers · License: CC BY 4.0
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evolutionary-biology
The distribution of fitness effects (DFE) of mutations is a key determinant of both the efficacy of natural selection and the genetic load of populations. It also provides an indirect summary of the underlying fitness landscape, so the extent to which the DFE is conserved across species is informati
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