bioRxiv / medRxiv
open access
CC BY-NC-ND 4.0
DeepPROTECTNeo: A Context-aware Personalized and Reverse Vaccinology-guided Deep Learning Framework for Immunogenicity Prediction
Background: The development of personalized cancer vaccines relies on accurately identifying neoepitopes capable of eliciting strong immune responses. T cell receptor (TCR)-epitope interactions are fundamental to cancer immunotherapy. Traditional computational approaches focus primarily on epitope-m
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