bioRxiv / medRxiv
open access
CC BY 4.0
MAP3K7 Loss of Function Causes Dilated Cardiomyopathy
Background and AimsDilated cardiomyopathy (DCM) is a genetically heterogeneous cause of heart failure and sudden cardiac death. Many patients remain without a molecular diagnosis. MAP3K7 encodes TAK1, a serine/threonine kinase important for cardiac homeostasis. MAP3K7 variants are an established cau
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