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VItamin K Inhibition and NeurocoGnition (VIKING)

University Hospital, Angers · 2017
ClinicalTrials.gov · Datasets · License: Public Domain · 2017
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neurocognitive-disorders
The primary objective of this study is to determine whether patients usually taking Vitamin K Antagonists (VKAs) exhibit a poorer global cognitive performance than control patients (matched on age, gender and indication for anticoagulation) taking direct oral anticoagulants (DOACs). The secondary objectives are: * to determine whether patients usually taking VKAs are more likely to have moderate to severe cognitive disorders than matched controls taking DOACs. * to determine whether VKAs intake is associated with poorer executive functions. * to determine on CT scans whether the VKAs intake is associated with a greater volume of vascular calcifications in the brain compared to the use of DOACs.
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