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ReACHallenge Trial: Acetylcholine Rechallenge After Pretreatment With Vasoactive Drugs

University Hospital, Antwerp · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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acetylcholinena
The goal of this clinical trial is to assess the feasibility and clinical value of acetylcholine (ACH) rechallenge after intracoronary verapamil +- nitroglycerine in a patient cohort with angina and non-obstructive coronary arteries (ANOCA). The main questions it aims to answer are: * to determine the efficacy of these drugs in treating ACH-induced coronary artery spasm * to determine the efficacy of these drugs in preventing ACH-induced coronary artery spasm The ACH rechallenge will take place during the index coronary function tests in patients with proven ACH-induced vasospastic angina. The study is considered a feasibility study, no control arm is included.
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