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A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Atreca, Inc. · 2020
ClinicalTrials.gov · Datasets · License: Public Domain · 2020
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breast-cancercolorectal-canceresophageal-squamous-cell-carcinomahead-and-neck-squamous-cell-carcinomahepatocellular-carcinomamelanomanon-small-cell-lung-cancerovarian-cancer
ATRC-101-A01 is a Phase 1b, open-label dose escalation and expansion trial of ATRC-101, an engineered fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally occurring human antibody. The safety, tolerability, PK, and biological activity of ATRC-101 will be characterized when administered every two weeks (Q2W) or every 3 weeks (Q3W) as a monotherapy or in combination with other anticancer agents.
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