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Mechanistic Studies of Phase III Trial With BAF312 in Secondary Progressive Multiple Sclerosis

National Institute of Allergy and Infectious Diseases (NIAID) · 2014
ClinicalTrials.gov · Datasets · License: Public Domain · 2014
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autoimmunityclinical-research
The primary goal of this study is to evaluate the effects of BAF312 (siponimod) on select immune and neuronal (nerve) cells by examining laboratory specimens (blood and/or spinal fluid) at multiple time points, prior to, and following the initiation of BAF312 or placebo treatment, in patients with Secondary Progressive Multiple Sclerosis (SPMS) who are enrolled in a clinical trial (NCT01665144) to evaluate the effectiveness and safety of BAF312.
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