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Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers

Yale University · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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alzheimer-diseaseanxietycaregiverdementiaeegmild-cognitive-impairment
This study aims to investigate the neurophysiological effects of live music on individuals with early Alzheimer's Disease (AD), dementia, and/or mild cognitive impairment (MCI) and their caregivers. Heart rate (HR), heart rate variability (HRV), and brain activity will be measured as participant-caregiver dyads listen to preferred and improvised music performed by professional musicians. Investigators will leverage various measurement techniques including, but not limited to, electroencephalography (EEG), behavioral, surveys, and physiological monitoring to study the impact of live music on anxiety in AD and inter-dyad synchrony.
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