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Dynamism and evolvability in nucleic acid enzymes

Lee, Erica M et al.
eScholarship · Papers
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31-biological-sciences-for-2020dnaevolution
Protein dynamism and evolvability are key parameters linking enzyme flexibility to adaptive potential, yet how these concepts apply to nucleic acid enzymes remains largely unexplored. Here, we propose that threose nucleic acid (TNA), a genetic polymer that is more conformationally restricted than DN
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