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Examining iron‐related off‐target binding effects of 18F‐AV1451 PET in the cortex of Aβ+ individuals
The presence of neurofibrillary tangles containing hyper-phosphorylated tau is a characteristic of Alzheimer's disease (AD) pathology. The positron emission tomography (PET) radioligand sensitive to tau neurofibrillary tangles (18F-AV1451) also binds with iron. This off-target binding effect may be
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