HAL (France)
open access
Culture-dependent decoupling of <i>H19</i> allele-specific expression from <i>H19/IGF2</i> :IG-DMR methylation in experimental models
Genomic imprinting is an epigenetic mechanism leading to the monoallelic expression of a subset of genes, mainly regulated by DNA methylation at imprinting control regions (ICRs). Silver-Russell syndrome (SRS) is a paradigmatic imprinting disorder in which loss of methylation at the 11p15.5
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