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Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning

Schwayer, Cornelia ; https://orcid.org/0000-0001-5130-2226 et al.
ISTA Publications · Papers
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heterogeneitymechanicsmodelingorganoids
Tissue regeneration requires de novo patterning, which has been proposed to be facilitated by cellular heterogeneity. Yet how such heterogeneities are integrated with the mechanochemical state of the tissue and stabilized at the chromatin level into stable, spatially organized fates remains poorly u
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