bioRxiv / medRxiv
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CC BY 4.0
A Transcriptionally Distinct Intermediate Activation State Precedes Langerhans Cell Migration from the Epidermis
Langerhans cells (LC) are antigen-presenting cells that form dense epidermal networks for immune surveillance. Upon antigen uptake, LCs are activated and subsequently orchestrate immune responses by migrating into the lymphatic system. However, the regulation of transcriptional programs during activ
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