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MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

M.D. Anderson Cancer Center · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
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This phase I trial studies best dose and side effects of oncolytic adenovirus DNX-2401 in treating patients with high-grade glioma that has come back (recurrent). Oncolytic adenovirus DNX-2401 is made from the common cold virus that has been changed in the laboratory to make it less likely to cause an infection (such as a cold). The virus is also changed to target brain cancer cells and attack them.
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