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A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

AstraZeneca · 2024
ClinicalTrials.gov · Datasets · License: Public Domain · 2024
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advanced-solid-tumorgastric-cancerhead-and-neck-squamous-cell-carcinomanon-small-cell-lung-cancerpancreatic-ductal-adenocarcinomarenal-cell-carcinoma
This is a first-in-human, Phase 1, non-randomized, multicenter, open-label clinical study designed to investigate the safety, tolerability, dosimetry, biodistribution, and pharmacokinetics (PK) of \[225Ac\]-FPI-2068, \[111In\]-FPI-2107, and FPI-2053 in metastatic and/or recurrent solid tumors (HNSCC, NSCLC, mCRC, PDAC, GC, RCC).
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