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Sortilin exhibits tumor suppressor-like activity by limiting EGFR transduction function

E. Lapeyronnie et al.
HAL (France) · Papers
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Abstract Lung cancer is the leading cause of cancer deaths worldwide and remains one of the most difficult to cure. Tyrosine kinase receptors, such as the epidermal growth factor receptor (EGFR), are often aberrantly activated by gene mutation and drive tumor growth. Monotherapy with tyrosine kinase
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