HAL (France)
open access
Inhibition of HIV-1 replication by primer RNA packaging inhibitors
ABSTRACT An essential step in the life cycle of human immunodeficiency virus type 1 (HIV-1) is the packaging of tRNA 3 Lys during viral assembly. This step, which requires the assembly of a ternary complex consisting of GagPol, mitochondrial lysyl-tRNA synthetase, and tRNA 3 Lys , is essential for t
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