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CardamomOT: A mechanistic optimal transport-based framework for gene regulatory network inference, trajectory reconstruction and generative modeling

Yann Maugé et al.
PLOS · Papers · License: CC BY 4.0
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cell-differentiationgene-expressiongene-regulationmessenger-rna
A key challenge in inferring gene regulatory networks (GRNs) governing cellular processes such as differentiation and reprogramming from experimental data lies in the impossibility of directly measuring protein dynamics at the single-cell level, which prevents establishing causal relationships betw
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