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Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or Neuroblastoma

Dana-Farber Cancer Institute · 2002
ClinicalTrials.gov · Datasets · License: Public Domain · 2002
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neuroblastomapediatric
RATIONALE: Thalidomide may stop the growth of tumor cells by stopping blood flow to the tumor. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining thalidomide with temozolomide may kill more tumor cells. PURPOSE: This phase II trial is studying the effectiveness of combining thalidomide with temozolomide in treating young patients who have relapsed or progressive brain tumors or recurrent neuroblastoma.
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