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Light Therapy for Elderly Depression

GGZ Buitenamstel · 2003
ClinicalTrials.gov · Datasets · License: Public Domain · 2003
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elderlyhpa-axismajor-depressive-disordermelatoninrandomized-controlled-trialself-efficacysocial-support
The purpose of this study is to investigate the following two hypotheses: 1. Treatment with bright light improves their sleep, mood, concentration and self-sufficiency of elderly depressed subjects. This clinical improvement is accompanied by decreases in cortisol/DHEA ratio and increases in melatonin concentration in urine and saliva. 2. The eventual beneficial effect of bright light treatment can be predicted by the presence of sleep-wake rhythm disturbances as found using muscle activity registration, and by cortisol/DHEA and melatonin concentrations in saliva and urine over the day and the night.
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