HAL (France)
open access
DNA G-Quadruplex Is a Transcriptional Control Device That Regulates Memory
The conformational state of DNA fine-tunes the transcriptional rate and abundance of RNA. Here, we report that G-quadruplex DNA (G4-DNA) accumulates in neurons, in an experience-dependent manner, and that this is required for the transient silencing and activation of genes that are critically involv
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