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Rap1‐suppressed tumorigenesis is concomitant with the interference in Ras effector signaling

Yea-Lih Lin et al.
HAL (France) · Papers
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Expression of Rap1 blocks epithelial growth factor‐induced extracellular signal‐regulated kinases (ERKs) activation. However, recent studies demonstrated that Rap1 mediates ERKs activation induced by nerve growth factor. The anti‐oncogenic effect of Rap1 has been reported but its mechanism remains u
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