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Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

Gaia Scilironi et al.
HAL (France) · Papers
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bordetella-pertussis
The adenylate cyclase toxin (CyaA) from Bordetella pertussis intoxicates host cells by directly translocating its N‐terminal catalytic domain across the plasma membrane; however, the forces driving this unique process remain poorly defined. Here, we dissect the membrane translocation mechanisms of t
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