HAL (France)
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HepaRGTM CYP induction test method augmentation part 1: The GOLIATH Study
Cytochrome P450 (CYP) enzymes play a key role in the metabolism of both xenobiotics and endogenous com-pounds, and some CYP isoforms are susceptible to induction and/or inhibition by certain chemicals. As CYP induction/inhibition can significantly alter the in vivo fate of xenobiotics, i.e., levels
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