Sirtuin 7 regulates dosage compensation and safeguards the female X-chromosome

Sirtuin 7 regulates dosage compensation and safeguards the female X-chromosome | Zenodo Skip to main Communities My dashboard Log in Sign up Published April 9, 2026 | Version v2 Software Open Sirtuin 7 regulates dosage compensation and safeguards the female X-chromosome Authors/Creators Simonet, Nicolas (Researcher) 1 Thackray, Joshua K (Researcher) 2 Kesner, Barry (Researcher) 1 Guitart-Solanes, Anna (Researcher) 3 Serra, François (Researcher) 4 Espinosa-Alcantud, Maria (Researcher) 3 Lappala, Anna (Researcher) 1 Marín-Gual, Laia (Researcher) 5, 6 Marín-García, Cristina (Researcher) 5, 6 Weissbein, Uri (Researcher) 1 et al. Show all 22 authors Authors/Creators 22 / 22 Simonet, Nicolas (Researcher) 1 Thackray, Joshua K (Researcher) 2 Kesner, Barry (Researcher) 1 Guitart-Solanes, Anna (Researcher) 3 Serra, François (Researcher) 4 Espinosa-Alcantud, Maria (Researcher) 3 Lappala, Anna (Researcher) 1 Marín-Gual, Laia (Researcher) 5, 6 Marín-García, Cristina (Researcher) 5, 6 Weissbein, Uri (Researcher) 1 Castelló-García, Josema (Researcher) 3 Bauer, Moritz (Researcher) 7 Wang, Danni (Researcher) 1 Rovirosa, Llorenç (Researcher) 4 Tischfield, Jay (Researcher) 2 Serrano, Lourdes (Researcher) 2, 8 Payer, Bernhard (Researcher) 7 Ruiz-Herrera, Aurora (Researcher) 5, 6 Vazquez, Berta (Researcher) 3, 5 Javierre, Biola (Researcher) 4 Vaquero, Alejandro (Researcher) 3 Lee, Jeannie (Researcher) 1 1.

Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA 2.

Human Genetics Institute of New Jersey (HGINJ), Department of Genetics, Rutgers University, 145 Bevier Rd., Piscataway, NJ, 08854, USA 3.

Chromatin Biology Laboratory, Josep Carreras Leukaemia Research Institute (IJC), Ctra de Can Ruti, Camí de les Escoles s/n, 08916, Badalona, Barcelona, Spain 4.

3D Chromatin Organization Group, Josep Carreras Leukaemia Research Institute (IJC), Germans Trias I Pujol, Badalona, Spain 5.

Unitat de Citologia i d'Histologia, Departament de Biologia Cellular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona (UAB), Cerdanyola del Valles, 08193 Barcelona, Spain 6.

Genome Integrity and Instability Group, Institut de Biotecnología i Biomedicina, Universitat Autònoma de Barcelona (UAB), Cerdanyola del Valles, 08193 Barcelona, Spain 7.

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain 8.

Department of Science, BMCC, The City University of New York (CUNY), 199 Chambers Street N699P, New York, NY 10007, USA Close Description Downstream bioinformatics analysis related to publication.  Code, datasets, used for analysis or RNA-seq data include DE, normalization, GSEA, figure generation (ecdf, scatterplots, others) contained in "code.tgz". Code and additional datasets used for analysis of ChIP-seq experiments is contained in "ChIP_analyses.tar.gz". Files Files (81.5 MB) Name Size Download all ChIP_analyses.tar.gz md5:9e8563205a8ffd47b12b7a25b09ffc98 65.6 MB Download code.tgz md5:4d6ae350f1c48c6db9dfa6d078c8bd9e 15.9 MB Download readme md5:efdf2010509edcd7d5ad343170d4816f 178 Bytes Download Additional details Related works References Dataset:

GSE256284

(Other) Dataset:

GSE256285

(Other) Dataset:

GSE295586

(Other) Dates Created 2026-04-07 first upload Software Programming language R Development Status Unsupported References Simonet, N. G. et al. Sirtuin 7 regulates dosage compensation and safeguards the female X-chromosome, Nature pre-print 258 Views 67 Downloads Show more details All versions This version Views Total views 258 138 Downloads Total downloads 67 63 Data volume Total data volume 2.1 GB 2.1 GB More info on how stats are collected.... Versions External resources Indexed in OpenAIRE Communities Keywords and subjects Keywords Sirtuin 7 doage comensation X-chromosome Details DOI DOI Badge DOI 10.5281/zenodo.19484523 Markdown [](https://doi.org/10.5281/zenodo.19484523) reStructuredText .. image:: https://zenodo.org/badge/DOI/10.5281/zenodo.19484523.svg :target: https://doi.org/10.5281/zenodo.19484523 HTML <a href="https://doi.org/10.5281/zenodo.19484523"><img src="https://zenodo.org/badge/DOI/10.5281/zenodo.19484523.svg" alt="DOI"></a> Image URL https://zenodo.org/badge/DOI/10.5281/zenodo.19484523.svg Target URL https://doi.org/10.5281/zenodo.19484523 Resource type Software Publisher Zenodo Published in Nature, 2026. Languages English Rights License Creative Commons Attribution 4.0 International The Creative Commons Attribution license allows re-distribution and re-use of a licensed work on the condition that the creator is appropriately credited. Read more Citation Export Technical metadata Created April 10, 2026 Modified April 10, 2026 Jump up About About Policies Infrastructure Principles Projects Roadmap Contact Blog Blog Support Help FAQ Developers REST API OAI-PMH Contribute GitHub Donate Funded by Powered by CERN Data Centre & InvenioRDM Status Privacy policy Cookie policy Terms of Use This site uses cookies. Find out more on how we use cookies Accept all cookies Accept only essential cookies

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