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Parallel multi-response optimization of reflux and maceration extraction of Sargassum polycystum from the east coast of Pangandaran using Box–Behnken design
Sargassum polycystum contains phenolic- and flavonoid-reactive constituents, although extraction yield and antioxidant quality may respond differently to processing conditions. This study optimized reflux and maceration extraction using response surface methodology–Box–Behnken design and assessed yi
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