bioRxiv / medRxiv
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CC BY-NC-ND 4.0
FBXW11 Activity Regulates Radial Glial Expansion in Human Cerebral Organoids
Human brain development depends on tightly coordinated gene-regulatory programs and the emergence of complex tissue architecture, making large scale functional interrogation difficult using conventional screen models. To overcome this challenge, we used a pooled CRISPR screening approach. Guided by
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