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The Influence of Overfeeding Different Macronutrients on Whole-body Insulin Sensitivity

Loughborough University · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
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glucose-metabolism-disordersinsulin-resistancemetabolic-diseasenatype-2-diabetes
This study will investigate the effect of high-carbohydrate vs. high-fat overfeeding (130% of energy requirements) on whole body insulin sensitivity. Following habitual diet, participants will be randomly allocated to either a high-carbohydrate or a high-fat diet intervention for 14-days. On days 0, 7 and 14 participants will undergo anthropometric and metabolic testing (primarily an oral glucose tolerance test \[OGTT\]).
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