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Minimum Local Anesthetic Volume of Bupivacaine in Labour Epidurals

Samuel Lunenfeld Research Institute, Mount Sinai Hospital · 2005
ClinicalTrials.gov · Datasets · License: Public Domain · 2005
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Different medications can be used as analgesics in labor epidurals. Bupivacaine is one of the most commonly used drugs for that purpose. The efficacy of a certain medication injected epidurally depends on the dose that is given. A certain dose can be administered in different concentrations, which will consequently mean different volumes. Our hypothesis is that for each concentration of a certain drug, there has to be a minimum effective volume that will be associated with the best possible performance of the drug. This study is being conducted to find the minimum volume of bupivacaine (a local anesthetic) that produces successful analgesia in 95% of patients in labor.
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