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Xenin-25: Novel Regulator of Insulin Secretion and Beta-cell Function

Washington University School of Medicine · 2009
ClinicalTrials.gov · Datasets · License: Public Domain · 2009
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blood-sugardiabetesinsulintype-2-diabetes-mellitus
An intestinal hormone called Glucose-dependent Insulinotropic Polypeptide (GIP) is released into the blood immediately after ingestion of a meal and plays an important role in regulating blood sugar levels. However, GIP is not active in persons with type 2 diabetes mellitus (T2DM) which is also known as adult onset or non-insulin-dependent diabetes. This study is being conducted to determine whether a hormone called xenin-25 can restore the activity of GIP in persons with T2DM.
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