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Physiological and Psychosomatic Effects of Exposure to MRI Scanning Environment

National Institute of Neurological Disorders and Stroke (NINDS) · 2014
ClinicalTrials.gov · Datasets · License: Public Domain · 2014
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healthy-volunteersmri
Background: \- Magnetic resonance imaging (MRI) creates high-quality images of the human body without x-rays. It uses a strong magnetic field and radio waves to take pictures. Researchers want to test a scanner that uses a high magnetic field strength. Objective: \- To study how the body responds to being in a high field 11.7T MRI scanner. Eligibility: \- Healthy people ages 22 65. Design: * Participants will be screened with a medical history and physical exam. They will complete a healthy volunteer questionnaire and an MRI safety screening form. They may have a 3T MRI scan of the brain. * Participants will have an MRI scan. They will lie on a table that will slide in and out of the MRI cylinder very slowly. They will be asked to lie still. * Participants will do simple tasks while inside the machine. These can include listening and responding to questions, tapping fingers, or moving a hand. * While in the scanner, participants will hear loud knocking noises. They will get earmuffs. * Right when they exit the scanner, participants will get a questionnaire to fill out. This will ask about how they felt inside the scanner. * During the MRI, participants heart rate, respiratory rate, and skin temperature will be measured. Before and after the scan, these things plus blood pressure will be measured. * Participants will be tested before and after being in the MRI scanner. They will answer questions, take pen-and-paper or computer tests, and do simple actions. Their sense of smell may be tested.
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