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Downstream of β-catenin: A positive feedback loop between Goosecoid and Nodals in Spemann’s organizer
We report on the role of the homeobox gene goosecoid (gsc) within an epistatic pathway that mediates body axis formation in Xenopus. Embryos depleted of β-catenin form exclusively ventral structures and lack all traces of axial structures. Microinjection of gsc mRNA rescues an entire body axis with
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