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Probing the Structure and Dynamics of Telomeric G‑Quadruplexes with Thienoguanosine, a Fluorescent Analogue of Guanosine
The potential of thienoguanosine (thG), an isomorphic fluorescent analogue of guanosine, was evaluated as a reporter for probing the structure and dynamics of hTel22, a human telomeric G-quadruplex (G4) sequence. Nine of the 12 guanines directly participating in G-tetrads were individually substitut
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