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Fluorescent cAMP Analogs: Enzymatic Synthesis, Unexpected Photophysical Behavior and Protein Kinase A Recognition

Cong, Deyuan et al.
eScholarship · Papers · License: CC BY
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31-biological-sciences-for-2020
ABSTRACT Cyclic adenosine monophosphate (cAMP) is a second messenger, regulating critical physiological processes. We report the enzymatic synthesis, unique photophysical features, and biological activity of novel emissive cAMP analogs (c th AMP and c tz AMP), comprised of thiopheno‐ and isothiazol
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