HAL (France)
open access
ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis
Significance Inflammation regulation and homeostasis maintenance is of paramount importance for lung health. Using both genetic and pathological mouse models, this work reveals that the secreted proapoptotic isthmin 1 (ISM1) protects lung homeostasis by controlling alveolar macrophage (AM) populatio
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