HAL (France)
open access
PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC
Abstract The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) is a regulatory hub for transcription and RNA processing. Here, we identify PHD-finger protein 3 (PHF3) as a regulator of transcription and mRNA stability that docks onto Pol II CTD through its SPOC domain. We
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