HAL (France)
open access
Glycans located upstream of the furin cleavage site in SARS-CoV-2 Spike protein influence its processing and functions
The SARS-CoV-2 Spike (S) glycoprotein, which plays a central role in viral entry, consists of two subunits: S1, which mediates binding to the ACE2 receptor; and S2, which induces fusion of the viral envelope with the cell membrane. The S glycoprotein also contains a polybasic motif at the S1/S2 junc
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