Biallelic PIGB Variants Cause Motor Neuropathy with Conduction Blocks and Peripheral Nerve Hyperexcitability

Objective Glycosylphosphatidylinositol ( GPI )‐anchored proteins play critical roles in nervous system function. Pathogenic variants in genes involved in GPI ‐anchor biosynthesis cause early‐onset multisystem disorders known as inherited GPI deficiencies. We describe a novel neuromuscular phenotype