Loss of Cyclin G–Associated Kinase Leads to Lysosome Dysfunction and Immune Modulation in Podocytes

Key Points Loss of podocyte-associated cyclin G–associated kinase resulted in mistrafficking of lysosomal hydrolases. Loss of podocyte-associated cyclin G–associated kinase induced immune modulation. Background Given the postmitotic nature of podocytes, adapting to both physiologic and pathologic st