HAL (France)
open access
CXCR4 dysfunction in non-alcoholic steatohepatitis in mice and patients
Homing of inflammatory cells to the liver is key in the progression of non-alcoholic steatohepatitis (NASH). An abnormal response of CD4+ T-cells from obese mice to the chemotactic effect of CXCL12 has been reported but the mechanism involved in this process and relevance in patients are unknown. We
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