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Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice

Valérie Besnard et al.
HAL (France) · Papers
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ATP-binding cassette A3 (ABCA3) is a lipid transport protein required for synthesis and storage of pulmonary surfactant in type II cells in the alveoli. Abca3 was conditionally deleted in respiratory epithelial cells ( Abca3 Δ/Δ ) in vivo. The majority of mice in which Abca3 was deleted in alveolar
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